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clopimozide

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clopimozide

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Also known as R-29,764

Clopimozide (R-29,764) is a typical antipsychotic drug of the diphenylbutylpiperidine class. It is very potent and has an extremely long duration of action, lasting at least one week with a single dose. It was developed by Janssen Pharmaceutica but was never marketed. == See also == Typical antipsychotic Diphenylbutylpiperidine

Chemical data

Formula
C28H28ClF2N3O
Molecular weight
496 g/mol
IUPAC name
3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-6-chloro-1H-benzimidazol-2-one
SMILES
C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F
InChIKey
JCZYXTVBWHAWLL-UHFFFAOYSA-N
XLogP
6.9
Polar surface area
35.6 Ų
H-bond donors
1
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
495.189
Show 3 more facts
chemical formula
C₂₈H₂₈ClF₂N₃O
canonical SMILES
C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F
Commons category
Clopimozide
Sources (2)

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Encyclopedic overview

2 sections
Contents
  • See also
  • References

Clopimozide (R-29,764) is a typical antipsychotic drug of the diphenylbutylpiperidine class. It is very potent and has an extremely long duration of action, lasting at least one week with a single dose. It was developed by Janssen Pharmaceutica but was never marketed. == See also == Typical antipsychotic Diphenylbutylpiperidine

== References ==

Excerpted from Wikipedia’s “clopimozide” article, available under the CC BY-SA 4.0 licence.

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