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GeneQ18042782· pop 6· linked from 4 articles

Also known as ARCA2, CABC1, COQ10D4, COQ8, SCAR9, ADCK3, aarF domain containing kinase 3, coenzyme Q8A

aarF domain containing kinase 3 is a protein that in humans is encoded by the ADCK3 gene.

Gene data

COQ8A
Name
coenzyme Q8A
Type
protein-coding
Position
226,938,143–226,987,569 (+)
Aliases
ADCK3, ARCA2, CABC1, COQ10D4, COQ8, SCAR9
RefSeq RNA
NM_020247.5, XM_005273201.2, XM_011544238.2, XM_011544239.3, XM_024448517.2
RefSeq protein
NP_064632.2, XP_005273258.1, XP_011542540.1, XP_011542541.1, XP_024304285.1

This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined. [provided by RefSeq, Jul 2008].

via MyGene.info

Wikidata facts

Show 5 more facts
HomoloGene ID
11345
genomic start
226940286
genomic end
226987544
cytogenetic location
1q42.13
Sources (5)

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aarF domain containing kinase 3 is a protein that in humans is encoded by the ADCK3 gene.

This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.

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