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GeneQ18028427· pop 5· linked from 5 articles

Also known as LAF4, MLLT2-like, AF4/FMR2 family member 3, KINS

AF4/FMR2 family member 3 is a protein that in humans is encoded by the AFF3 gene.

Gene data

AFF3
Name
ALF transcription elongation factor 3
Type
protein-coding
Aliases
KINS, LAF4, MLLT2-like

This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008].

via MyGene.info

Wikidata facts

Show 5 more facts
HomoloGene ID
1718
genomic start
99545419
genomic end
100192428
cytogenetic location
2q11.2
Sources (5)

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Article

4 sections
Contents
  • Function
  • References
  • External links
  • Further reading

AF4/FMR2 family member 3 is a protein that in humans is encoded by the AFF3 gene.

== Function ==

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