CREG1
Sign in to saveAlso known as CREG, cellular repressor of E1A stimulated genes 1
Protein CREG1 (Cellular Repressor of E1A-stimulated Genes 1) is a protein that in humans is encoded by the CREG1 gene.
Gene data
CREG1- Name
- cellular repressor of E1A stimulated genes 1
- Type
- protein-coding
- Aliases
- CREG
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
- Image
- Protein CREG1 PDB 1xhn.png
Show 5 more facts
- HomoloGene ID
- 31199
- exact match
- identifiers.org/ncbigene/8804
- genomic end
- 167553805
- genomic start
- 167529117
- cytogenetic location
- 1q24.2
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Protein CREG1 (Cellular Repressor of E1A-stimulated Genes 1) is a protein that in humans is encoded by the CREG1 gene.
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.