CREG1
Sign in to saveAlso known as CREG, cellular repressor of E1A stimulated genes 1
Protein CREG1 (Cellular Repressor of E1A-stimulated Genes 1) is a protein that in humans is encoded by the CREG1 gene.
In the Vinony graph
Vinony's link graph records 3 inbound references to CREG1, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 1.
Vinony links it to 7 Wikipedia language editions.
Gene data
CREG1- Name
- cellular repressor of E1A stimulated genes 1
- Type
- protein-coding
- Position
- 167,527,807–167,553,822 (−)
- Aliases
- CREG
- Ensembl
- ENSG00000143162
- RefSeq RNA
- NM_003851.3
- RefSeq protein
- NP_003842.1
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
via MyGene.info
Gene · Ensembl
cellular repressor of E1A stimulated genes 1
- Symbol
- CREG1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:167,527,807-167,553,822
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CREG1 PDB 1xhn.png
Show 8 more facts
- HomoloGene ID
- 31199
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8804
- genomic end
- 167553805
- genomic start
- 167529117
- chromosome
- human chromosome 1
- cytogenetic location
- 1q24.2
- expressed in
- trabecular bone
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Protein CREG1 (Cellular Repressor of E1A-stimulated Genes 1) is a protein that in humans is encoded by the CREG1 gene.
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.
Excerpted from Wikipedia’s “CREG1” article, available under the CC BY-SA 4.0 licence.