CRTC1
Sign in to saveAlso known as MECT1, TORC-1, TORC1, WAMTP1, CREB regulated transcription coactivator 1, MAML2, Mam-2
CREB-regulated transcription coactivator 1 (CRTC1), previously referred to as TORC1 (), is a protein that in humans is encoded by the CRTC1 gene. It is expressed in a limited number of tissues that include fetal brain and liver and adult heart, skeletal muscles, liver and salivary glands and various regions of the adult central nervous system.
Gene data
CRTC1- Name
- CREB regulated transcription coactivator 1
- Type
- protein-coding
- Position
- 18,683,575–18,782,333 (+)
- Aliases
- MAML2, MECT1, Mam-2, TORC-1, TORC1, WAMTP1
- Ensembl
- ENSG00000105662
- RefSeq RNA
- NM_001098482.2, NM_015321.3, NM_025021.1
- RefSeq protein
- NP_001091952.1, NP_056136.2
Enables cAMP response element binding protein binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol; nuclear body; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
CREB regulated transcription coactivator 1
- Symbol
- CRTC1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:18,683,575-18,782,333
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
5 sectionsContents
- Clinical significance
- See also
- References
- Further reading
- External links
CREB-regulated transcription coactivator 1 (CRTC1), previously referred to as TORC1 (), is a protein that in humans is encoded by the CRTC1 gene. It is expressed in a limited number of tissues that include fetal brain and liver and adult heart, skeletal muscles, liver and salivary glands and various regions of the adult central nervous system.
== Clinical significance ==
Excerpted from Wikipedia’s “CRTC1” article, available under the CC BY-SA 4.0 licence.