RNF14

Name

ring finger protein 14

Type

protein-coding

Position

141,958,305–142,003,016 (+)

Aliases

ARA54, HFB30, HRIHFB2038, TRIAD2

Ensembl

ENSG00000013561

RefSeq RNA

NM_001201365.2, NM_004290.5, NM_183398.3, NM_183399.3, NM_183400.3

RefSeq protein

NP_001188294.1, NP_004281.1, NP_899645.1, NP_899646.1, NP_899647.1

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011].

via MyGene.info

Gene · Ensembl

ring finger protein 14

Symbol

RNF14

Biotype

Protein coding

Organism

Homo sapiens

Location

5:141,958,305-142,003,016

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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