NCOR2

Name

nuclear receptor corepressor 2

Type

protein-coding

Position

124,324,407–124,567,647 (−)

Aliases

CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC-1, TRAC1

Ensembl

ENSG00000196498

RefSeq RNA

NM_001077261.4, NM_001206654.2, NM_006312.6

RefSeq protein

NP_001070729.2, NP_001193583.1, NP_006303.4

This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011].

via MyGene.info

Gene · Ensembl

nuclear receptor corepressor 2

Symbol

NCOR2

Biotype

Protein coding

Organism

Homo sapiens

Location

12:124,324,407-124,567,647

Strand

Reverse (−)

Assembly

GRCh38