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CX614

Structure via PubChem · Public domain (PubChem)

EntityQ5014876· pop 5· linked from 832 articles

Also known as BDP 37, CX 614, CX-614

CX-614 is an ampakine drug developed by Cortex Pharmaceuticals. It has been investigated for its effect on AMPA receptors.

Chemical data

Formula
C13H13NO4
Molecular weight
247.25 g/mol
IUPAC name
4,7,11-trioxa-16-azatetracyclo[8.7.0.03,8.012,16]heptadeca-1,3(8),9-trien-17-one
SMILES
C1CC2N(C1)C(=O)C3=CC4=C(C=C3O2)OCCO4
InChIKey
RQEPVMAYUINZRE-UHFFFAOYSA-N
XLogP
1.5
Polar surface area
48 Ų
H-bond donors
0
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
247.084458
Show 3 more facts
chemical formula
C₁₃H₁₃NO₄
Commons category
CX614
canonical SMILES
C1CC2N(C1)C(=O)C3=CC4=C(C=C3O2)OCCO4
Sources (2)

via Wikidata · CC0

~2 min read

Encyclopedic overview

2 sections
Contents
  • See also
  • References

CX-614 is an ampakine drug developed by Cortex Pharmaceuticals. It has been investigated for its effect on AMPA receptors.

Chronic CX-614 treatments produce rapid increases in the synthesis of the brain-derived neurotrophic factor BDNF which has very important effects on synaptic plasticity and may have applications in the treatment of neurodegenerative diseases such as Alzheimer's disease.

Excerpted from Wikipedia’s “CX614” article, available under the CC BY-SA 4.0 licence.

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