Skip to content
CX546

Structure via PubChem · Public domain (PubChem)

EntityQ5014874· pop 5· linked from 853 articles

Also known as CX 546, CX-546

CX-546 is an ampakine drug developed by Cortex Pharmaceuticals.

Chemical data

Formula
C14H17NO3
Molecular weight
247.29 g/mol
IUPAC name
2,3-dihydro-1,4-benzodioxin-6-yl(piperidin-1-yl)methanone
SMILES
C1CCN(CC1)C(=O)C2=CC3=C(C=C2)OCCO3
InChIKey
LJUNPHMOGNFFOS-UHFFFAOYSA-N
XLogP
1.1
Polar surface area
38.8 Ų
H-bond donors
0
H-bond acceptors
3
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
247.120843
Show 2 more facts
chemical formula
C₁₄H₁₇NO₃
canonical SMILES
C1CCN(CC1)C(=O)C2=CC3=C(C=C2)OCCO3
Sources (2)

via Wikidata · CC0

~2 min read

Encyclopedic overview

2 sections
Contents
  • See also
  • References

CX-546 is an ampakine drug developed by Cortex Pharmaceuticals.

It has been proposed as a treatment for schizophrenia. CX-546 was the second drug of note to come out of the Cortex research program, after CX-516, but while it was an improvement over its predecessor in some respects, it still has problems with limited oral bioavailability.

Excerpted from Wikipedia’s “CX546” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0