dabrafenib
Sign in to saveDabrafenib, sold under the brand name Tafinlar among others, is an anti-cancer medication used for the treatment of cancers associated with a mutated version of the gene BRAF. Dabrafenib acts as an inhibitor of the associated enzyme B-Raf, which plays a role in the regulation of cell growth.
Key facts
- Drug.image
- Dabrafenib.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Dabrafenib-from-xtal-3D-bs-17.png
- Drug.image_class2
- bg-transparent
- Drug.width
- 200
- Drug.tradename
- Tafinlar
- Drug.MedlinePlus
- a613038
- Drug.DailyMedID
- Dabrafenib
- Drug.routes_of_administration
- By mouth
- Drug.ATC_prefix
- L01
- Drug.ATC_suffix
- EC02
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.legal_EU
- Rx-only
- Drug.legal_status
- Rx-only
- Drug.CAS_number
- 1195765-45-7
- Drug.PubChem
- 44462760
via Wikipedia infobox
Chemical data
- Formula
- C23H20F3N5O2S2
- Molecular weight
- 519.6 g/mol
- IUPAC name
- N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- +519.101
Show 4 more facts
- P2868
- antineoplastic
- P2175
- melanoma
- P366
- medication
- P769
- fosphenytoin
via Wikidata · CC0
Article
10 sectionsContents
- Medical uses
- History
- Society and culture
- Legal status
- United States
- European Union
- Brand names
- Research
- References
- Further reading
{{Infobox drug | image = Dabrafenib.svg | image_class = skin-invert-image | image2 = Dabrafenib-from-xtal-3D-bs-17.png | image_class2 = bg-transparent | width = 200 | alt = | alt2 = | caption =
| tradename = Tafinlar | Drugs.com = | MedlinePlus = a613038 | DailyMedID = Dabrafenib | pregnancy_AU = | pregnancy_category = | routes_of_administration = By mouth | ATCvet = | ATC_prefix = L01 | ATC_suffix = EC02