DDX39A
Sign in to saveAlso known as BAT1, BAT1L, DDX39, DDXL, URH49, DEAD-box helicase 39A, DExD-box helicase 39A
ATP-dependent RNA helicase DDX39 is an enzyme that in humans is encoded by the DDX39 gene.
Gene data
DDX39A- Name
- DExD-box helicase 39A
- Type
- protein-coding
- Position
- 14,408,798–14,419,383 (−)
- Aliases
- BAT1, BAT1L, DDX39, DDXL, URH49
- Ensembl
- ENSG00000123136
- RefSeq RNA
- NM_001204057.1, NM_005804.4, NM_138998.1, NR_038336.1, NR_046366.2
- RefSeq protein
- NP_005795.2, XP_011525922.1, XP_054175470.1
This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is thought to play a role in the prognosis of patients with gastrointestinal stromal tumors. A pseudogene of this gene is present on chromosome 13. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Wikidata facts
- Image
- Protein DDX39 PDB 1t5i.png
Show 5 more facts
- HomoloGene ID
- 68487
- exact match
- identifiers.org/ncbigene/10212
- genomic end
- 14530192
- genomic start
- 14408798
- cytogenetic location
- 19p13.12
Sources (3)
via Wikidata · CC0
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Article
4 sectionsContents
- Clinical Significance
- References
- Further reading
- External links
ATP-dependent RNA helicase DDX39 is an enzyme that in humans is encoded by the DDX39 gene.
This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.