DDX19B
Sign in to saveAlso known as DBP5, DDX19, RNAh, DEAD-box helicase 19B
ATP-dependent RNA helicase DDX19B is an enzyme that in humans is encoded by the DDX19B gene.
Gene data
DDX19B- Name
- DEAD-box helicase 19B
- Type
- protein-coding
- Position
- 70,289,663–70,335,305 (+)
- Aliases
- DBP5, DDX19, RNAh
- Ensembl
- ENSG00000157349
- RefSeq RNA
- NM_001014449.3, NM_001014451.3, NM_001257172.2, NM_001257173.2, NM_001257174.2
- RefSeq protein
- NP_001014449.1, NP_001014451.1, NP_001244101.1, NP_001244102.1, NP_001244103.1
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Wikidata facts
- Image
- Protein DDX19B PDB 3EWS.png
Show 5 more facts
- HomoloGene ID
- 56032
- exact match
- identifiers.org/ncbigene/11269
- genomic end
- 70335305
- genomic start
- 70323566
- cytogenetic location
- 16q22.1
Sources (4)
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- Further reading
ATP-dependent RNA helicase DDX19B is an enzyme that in humans is encoded by the DDX19B gene.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.