DDX23
Sign in to saveAlso known as PRPF28, SNRNP100, U5-100K, U5-100KD, prp28, DEAD-box helicase 23
Probable ATP-dependent RNA helicase DDX23 is an enzyme that in humans is encoded by the DDX23 gene.
In the Vinony graph
Within Vinony's link graph, DDX23 is referenced by 2 other articles, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.
It sits within the topics Genes on human chromosome 12 and Spliceosome.
Its subject is documented across 4 Wikipedia language editions.
Gene data
DDX23- Name
- DEAD-box helicase 23
- Type
- protein-coding
- Position
- 48,829,756–48,852,842 (−)
- Aliases
- PRPF28, SNRNP100, U5-100K, U5-100KD, prp28
- Ensembl
- ENSG00000174243
- RefSeq RNA
- NM_004818.3
- RefSeq protein
- NP_004809.2
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
DEAD-box helicase 23
- Symbol
- DDX23
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:48,829,756-48,852,842
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 3542
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9416
- genomic end
- 49246625
- genomic start
- 48829756
- chromosome
- human chromosome 12
- cytogenetic location
- 12q13.12
- expressed in
- transverse colon
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Probable ATP-dependent RNA helicase DDX23 is an enzyme that in humans is encoded by the DDX23 gene.
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.
Excerpted from Wikipedia’s “DDX23” article, available under the CC BY-SA 4.0 licence.