DDX10
Sign in to saveAlso known as HRH-J8, DEAD-box helicase 10, Dbp4
Probable ATP-dependent RNA helicase DDX10 is an enzyme that in humans is encoded by the DDX10 gene.
In the Vinony graph
Within Vinony's link graph, DDX10 is referenced by 2 other articles, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 11.
Its subject is documented across 5 Wikipedia language editions.
Gene data
DDX10- Name
- DEAD-box helicase 10
- Type
- protein-coding
- Position
- 108,665,053–108,940,999 (+)
- Aliases
- Dbp4, HRH-J8
- Ensembl
- ENSG00000178105
- RefSeq RNA
- NM_004398.4
- RefSeq protein
- NP_004389.2
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
DEAD-box helicase 10
- Symbol
- DDX10
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:108,665,053-108,940,999
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein DDX10 PDB 2pl3.png
Show 7 more facts
- HomoloGene ID
- 20922
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1662
- genomic end
- 108940999
- genomic start
- 108665058
- chromosome
- human chromosome 11
- cytogenetic location
- 11q22.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Probable ATP-dependent RNA helicase DDX10 is an enzyme that in humans is encoded by the DDX10 gene.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies.
Excerpted from Wikipedia’s “DDX10” article, available under the CC BY-SA 4.0 licence.