Structure via PubChem · Public domain (PubChem)
decamethonium
Sign in to saveAlso known as N,N,N,N',n',n'-hexamethyl-1,10-decanediaminium, Decamethylenebis(trimethylammonium), DECAMETHONIUM ion, Decamethonum, trimethyl-[10-(trimethylammonio)decyl]ammonium, trimethyl-[10-(trimethylazaniumyl)decyl]azanium
Decamethonium (Syncurine) is a depolarizing muscle relaxant or neuromuscular blocking agent, and is used in anesthesia to induce paralysis.
Chemical data
- Formula
- C16H38N2+2
- Molecular weight
- 258.49 g/mol
- IUPAC name
- trimethyl-[10-(trimethylazaniumyl)decyl]azanium
- SMILES
- C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C
- InChIKey
- MTCUAOILFDZKCO-UHFFFAOYSA-N
- XLogP
- 3.9
- Polar surface area
- 0 Ų
- H-bond donors
- 0
- H-bond acceptors
- 0
- Formal charge
- 2
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1982
- Admin. routes
- parenteral
via ChEMBL · EBI
Research
1,164 papers- Muscle relaxants--decamethonium.Anaesthesia and intensive care · 2005
- DECAMETHONIUM IODIDE.Lancet (London, England) · 1963
- Amide naphthotube as a novel supramolecular sequestration agent for tetracaine and decamethonium.Theranostics · 2024
- Block by depolarization.Acta anaesthesiologica Scandinavica · 1994
- The biological fate of decamethonium. In vivo and in vitro studies.Acta pharmacologica et toxicologica · 1972
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 258.303
- Has use
- medication
Show 3 more facts
- chemical formula
- C₁₆H₃₈N₂²⁺
- canonical SMILES
- C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C
- Commons category
- Decamethonium
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Pharmacology
- Contraindications/limitations
- See also
- References
Decamethonium (Syncurine) is a depolarizing muscle relaxant or neuromuscular blocking agent, and is used in anesthesia to induce paralysis.
== Pharmacology ==
Excerpted from Wikipedia’s “decamethonium” article, available under the CC BY-SA 4.0 licence.