Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C40H50N8O10
- Molecular weight
- 802.9 g/mol
- IUPAC name
- (2S)-N-[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide
via PubChem
Drug data · ChEMBL
- Molecule type
- Protein
via ChEMBL · EBI
Research
586 papers- Dermorphin tetrapeptide analogs as potent and long-lasting analgesics with pharmacological profiles distinct from morphine.Peptides · 2011
- The dermorphin peptide family.General pharmacology · 1996
- Dermorphin [D-Arg2, Lys4] (1-4) Amide Attenuates Burn Pain by Inhibiting TRPV1/NR2B Mediated Neuroinflammatory Signalling.Molecular neurobiology · 2025
- Dermorphin: A Missed Palliative Care Opportunity for Intrathecal Therapy in Oncological Patients?Pain medicine (Malden, Mass.) · 2019
- Rediscovery of old drugs: the forgotten case of dermorphin for postoperative pain and palliation.Journal of pain research · 2018
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 802.365
Show 6 more facts
- chemical formula
- C₄₀H₅₀N₈O₁₀
- canonical SMILES
- CC(C(=O)NC(CC1=CC=CC=C1)C(=O)NCC(=O)NC(CC2=CC=C(C=C2)O)C(=O)N3CCCC3C(=O)NC(CO)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)O)N
- isomeric SMILES
- C[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CO)C(=O)N)NC(=O)[C@H](CC4=CC=C(C=C4)O)N
- subject has role
- opioid
- found in taxon
- red-eyed tree frog
- Commons category
- Dermorphin
Sources (3)
via Wikidata · CC0
Article · Deutsch
Dermorphin ist ein starkes Opioidpeptid, das von der Haut eines südamerikanischen Frosches der Gattung Phyllomedusa gebildet wird und 1981 entdeckt wurde. Sein Name leitet sich ab aus altgriech. δέρμα derma ‚Haut‘ und dem Namen des Gottes der Träume, Morpheus (Μορφεύς, abgeleitet aus μορφή morphe ‚Gestalt, Form‘).
Abstract from DBpedia / Wikipedia · CC BY-SA