Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C40H50N8O10
- Molecular weight
- 802.9 g/mol
- IUPAC name
- (2S)-N-[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide
via PubChem
Drug data · ChEMBL
- Molecule type
- Protein
via ChEMBL · EBI
Research
586 papers- Dermorphin tetrapeptide analogs as potent and long-lasting analgesics with pharmacological profiles distinct from morphine.Peptides · 2011
- The dermorphin peptide family.General pharmacology · 1996
- Dermorphin [D-Arg2, Lys4] (1-4) Amide Attenuates Burn Pain by Inhibiting TRPV1/NR2B Mediated Neuroinflammatory Signalling.Molecular neurobiology · 2025
- Dermorphin: A Missed Palliative Care Opportunity for Intrathecal Therapy in Oncological Patients?Pain medicine (Malden, Mass.) · 2019
- Rediscovery of old drugs: the forgotten case of dermorphin for postoperative pain and palliation.Journal of pain research · 2018
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 802.365
Show 6 more facts
- chemical formula
- C₄₀H₅₀N₈O₁₀
- canonical SMILES
- CC(C(=O)NC(CC1=CC=CC=C1)C(=O)NCC(=O)NC(CC2=CC=C(C=C2)O)C(=O)N3CCCC3C(=O)NC(CO)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)O)N
- isomeric SMILES
- C[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CO)C(=O)N)NC(=O)[C@H](CC4=CC=C(C=C4)O)N
- subject has role
- opioid
- found in taxon
- red-eyed tree frog
- Commons category
- Dermorphin
Sources (3)
via Wikidata · CC0
Article · Español
La dermorfina es un hepta péptido con propiedades analgésicas en roedores y primates. La dermorfina, junto a otros péptidos como la deltorfina, es naturalmente producida por algunas ranas como la Phyllomedusa bicolor y Phyllomedusa sauvagei para protegerse de la colonización de microorganismos exógenos. Sus moléculas son parecidas a los opiáceos: * Estructura de la dermorfina: H-Tir-D-Ala-Fe-Gli-Tir-Pro-Ser-NH2 * Fórmula química: C40H50N8O10 * Peso molecular: 802,9 g/mol
Abstract from DBpedia / Wikipedia · CC BY-SA