dipivefrin
Sign in to saveAlso known as Propine®, Dipivefrine, 1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol, 4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate, (+-)-4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate, dipivalyl epinephrine, 4-[1-Hydroxy-2-(methylamino)ethyl]-O-phenylene divavalate, 1-(3',4'-Dipivaloyloxyphenyl)-2-methylamino-1-ethanol
Dipivefrine, or dipivefrin, also known as epinephrine pivalate and sold under the brand name Propine among others, is a sympathomimetic medication which is used in the treatment of open-angle glaucoma. It is available as a 0.1% ophthalmic solution (eye drop).
Research
197 papers- Dipivefrin: current concepts.Australian journal of ophthalmology · 1980
- Pilocarpine and dipivefrin.The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc · 1991
- A combination of levobunolol and dipivefrin for the treatment of glaucoma.Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
- Dipivefrin and echothiophate. Efficacy of combined use in human beings.Archives of ophthalmology (Chicago, Ill. : 1960) · 1981
- Dipivefrin and epinephrine treatment of elevated intraocular pressure: a comparative study.Archives of ophthalmology (Chicago, Ill. : 1960) · 1979
via PubMed
Wikidata facts
- Mass
- 351.205
Show 4 more facts
- chemical formula
- C₁₉H₂₉NO₅
- canonical SMILES
- CC(C)(C)C(=O)OC1=C(C=C(C=C1)C(CNC)O)OC(=O)C(C)(C)C
- World Health Organisation international non-proprietary name
- dipivefrine
- Commons category
- Dipivefrine
via Wikidata · CC0
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Article
10 sectionsContents
- Medical uses
- Contraindications
- Side effects
- Pharmacology
- Chemistry
- History
- Society and culture
- Names
- See also
- References
Dipivefrine, or dipivefrin, also known as epinephrine pivalate and sold under the brand name Propine among others, is a sympathomimetic medication which is used in the treatment of open-angle glaucoma. It is available as a 0.1% ophthalmic solution (eye drop).
Side effects of dipivefrine include local eye reactions among others. Dipivefrine is a prodrug of epinephrine (adrenaline) and hence acts as a non-selective adrenergic receptor agonist. It is a substituted phenethylamine and catecholamine and is an ester of epinephrine with much greater fat solubility.