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Eletriptan

Structure via PubChem · Public domain (PubChem)

EntityQ415032· pop 12· linked from 1,625 articles

Eletriptan

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Also known as UK 116044

Eletriptan, sold under the brand name Relpax and used in the form of eletriptan hydrobromide, is a second-generation triptan medication intended for treatment of migraine headaches. It is used as an abortive medication, blocking a migraine attack which is already in progress. Eletriptan is marketed and manufactured by Pfizer.

Chemical data

Formula
C22H26N2O2S
Molecular weight
382.5 g/mol
IUPAC name
5-[2-(benzenesulfonyl)ethyl]-3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-1H-indole
SMILES
CN1CCC[C@@H]1CC2=CNC3=C2C=C(C=C3)CCS(=O)(=O)C4=CC=CC=C4
InChIKey
PWVXXGRKLHYWKM-LJQANCHMSA-N
XLogP
4.1
Polar surface area
61.6 Ų
H-bond donors
1
H-bond acceptors
3
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Approved
Molecule type
Small molecule
First approval
2002
Admin. routes
oral
Indications
migraine disorder, migraine with aura, migraine without aura

via ChEMBL · EBI

Research

323 papers

via PubMed

Wikidata facts

Mass
382.171499
Has use
medication
Show 9 more facts
medical condition treated
migraine
chemical formula
C₂₂H₂₆N₂O₂S
significant drug interaction
linezolid
isomeric SMILES
CN1CCC[C@@H]1CC2=CNC3=C2C=C(C=C3)CCS(=O)(=O)C4=CC=CC=C4
canonical SMILES
CN1CCCC1CC2=CNC3=C2C=C(C=C3)CCS(=O)(=O)C4=CC=CC=C4
World Health Organisation international non-proprietary name
eletriptan
defined daily dose
40
Commons category
Eletriptan
Sources (3)

via Wikidata · CC0