Structure via PubChem · Public domain (PubChem)
escaline
Sign in to saveEscaline (E), also known as 3,5-dimethoxy-4-ethoxyphenethylamine, is a psychedelic drug of the phenethylamine and scaline families related to mescaline. It is the 4-ethoxy analogue of mescaline (3,4,5-trimethoxyphenethylamine) and the phenethylamine (non-α-methyl) analogue of 3C-E (3,5-dimethoxy-4-ethoxyamphetamine). The drug has been encountered as a novel designer drug.
Chemical data
- Formula
- C12H19NO3
- Molecular weight
- 225.28 g/mol
- IUPAC name
- 2-(4-ethoxy-3,5-dimethoxyphenyl)ethanamine
- SMILES
- CCOC1=C(C=C(C=C1OC)CCN)OC
- InChIKey
- RHOGRSKNWDNCDN-UHFFFAOYSA-N
- XLogP
- 1.2
- Polar surface area
- 53.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 225.136
Show 3 more facts
- canonical SMILES
- CCOC1=C(C=C(C=C1OC)CCN)OC
- chemical formula
- C₁₂H₁₉NO₃
- Commons category
- Escaline
Sources (2)
via Wikidata · CC0
~5 min read
Encyclopedic overview
16 sectionsContents
- Use and effects
- Interactions
- Pharmacology
- Pharmacodynamics
- Chemistry
- Synthesis
- Analogues
- History
- Society and culture
- Legal status
- Canada
- Sweden
- United States
- See also
- References
- External links
Escaline (E), also known as 3,5-dimethoxy-4-ethoxyphenethylamine, is a psychedelic drug of the phenethylamine and scaline families related to mescaline. It is the 4-ethoxy analogue of mescaline (3,4,5-trimethoxyphenethylamine) and the phenethylamine (non-α-methyl) analogue of 3C-E (3,5-dimethoxy-4-ethoxyamphetamine). The drug has been encountered as a novel designer drug.
==Use and effects== In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists escaline's dose range as 40 to 60mg orally. The duration is stated to be 8 to 12hours, whereas the onset is not described. Escaline is approximately 5- to 8-fold more potent than mescaline.
Excerpted from Wikipedia’s “escaline” article, available under the CC BY-SA 4.0 licence.