Gene data
EVPL- Name
- envoplakin
- Type
- protein-coding
- Position
- 76,004,379–76,027,465 (−)
- Aliases
- EVPK
- Ensembl
- ENSG00000167880
- RefSeq RNA
- NM_001320747.2, NM_001988.4
- RefSeq protein
- NP_001307676.1, NP_001979.2
This gene encodes a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. This gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against the encoded protein. [provided by RefSeq, Jul 2016].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
envoplakin
- Symbol
- EVPL
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:76,004,379-76,027,465
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 1506
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2125
- genomic end
- 76027306
- genomic start
- 74000583
- chromosome
- human chromosome 17
- cytogenetic location
- 17q25.1
- expressed in
- nipple
Sources (4)
via Wikidata · CC0