Structure via PubChem · Public domain (PubChem)
exatecan
Sign in to saveExatecan is a drug which is a structural analog of camptothecin with antineoplastic activity.
Chemical data
- Formula
- C24H22FN3O4
- Molecular weight
- 435.4 g/mol
- IUPAC name
- (10S,23S)-23-amino-10-ethyl-18-fluoro-10-hydroxy-19-methyl-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaene-5,9-dione
- SMILES
- CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O
- InChIKey
- ZVYVPGLRVWUPMP-FYSMJZIKSA-N
- XLogP
- 0.4
- Polar surface area
- 106 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
171 papersvia PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 435.159
- Has use
- medication
Show 4 more facts
- chemical formula
- C₂₄H₂₂FN₃O₄
- Commons category
- Exatecan
- isomeric SMILES
- CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O
- canonical SMILES
- CCC1(C2=C(COC1=O)C(=O)N3CC4=C5C(CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Exatecan is a drug which is a structural analog of camptothecin with antineoplastic activity.
A derivative is used in Trastuzumab deruxtecan.
Excerpted from Wikipedia’s “exatecan” article, available under the CC BY-SA 4.0 licence.
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