fibrinolysin
Sign in to saveAlso known as plasmin, bovine fibrinolysin, bovine plasmin
Fibrinolysin is an enzyme derived from plasma of bovine origin (plasmin) or extracted from cultures of certain bacteria. It is used locally only and exclusively together with the enzyme desoxyribonuclease (extracted from bovine pancreas). Fibrinolysin and desoxyribonuclease both act as lytic enzymes. The combination is available as ointment containing 1 BU (Biological Unit) fibrinolysin and 666 BUs desoxyribonuclease per gram.
Research
9,286 papers- Fibrinolysin.Memphis and Mid-South medical journal · 1962
- [FIBRINOLYSIN].Harefuah · 1960
- [Fibrinolysin].La Revue de medecine · 1960
- [Fibrinolysin].Naika. Internal medicine · 1965
- Emphasis--fibrinolysin.Virginia medical monthly · 1967
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Has part
- carbon
- Has use
- medication
Show 1 more fact
- has characteristic
- biopharmaceutical
via Wikidata · CC0
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Encyclopedic overview
6 sectionsContents
- Indications
- Contraindications and precautions
- Side-effects
- Interactions
- See also
- External links
Fibrinolysin is an enzyme derived from plasma of bovine origin (plasmin) or extracted from cultures of certain bacteria. It is used locally only and exclusively together with the enzyme desoxyribonuclease (extracted from bovine pancreas). Fibrinolysin and desoxyribonuclease both act as lytic enzymes. The combination is available as ointment containing 1 BU (Biological Unit) fibrinolysin and 666 BUs desoxyribonuclease per gram.
Fibrinolysin attacks and inactivates fibrin molecules occurring in undesirable exudates on the surface of the human body and on human mucosa, e.g., in superficial wounds and burns, while desoxyribonuclease targets and destroys (human) DNA. The combination of the two enzymes has a synergistic effect on necrotic but not on living tissue. According to the manufacturer the ointment provides enhanced wound cleaning and accelerates the healing process.
Excerpted from Wikipedia’s “fibrinolysin” article, available under the CC BY-SA 4.0 licence.