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Structure via PubChem · Public domain (PubChem)
fluminorex
Sign in to saveFluminorex is a centrally acting sympathomimetic which is related to other drugs such as aminorex and pemoline. It was developed as an appetite suppressant by McNeil Laboratories in the 1950s. ==Synthesis== class=skin-invert-image|500px|thumb|center|Synthesis: Patent (Ex XV): 2-amino-1-[4-(trifluoromethyl)phenyl]ethanol [776-02-3] (1) cyanogen bromide [506-68-3] (2)
In the Vinony graph
Vinony's link graph records 1,490 inbound references to fluminorex, and connects out to D-methamphetamine, Anatomical Therapeutic Chemical Classification System and indopan.
It is catalogued under topics including Aminorexes, Chemical pages without DrugBank identifier and Drugs not assigned an ATC code.
Vinony links it to 5 Wikipedia language editions.
Chemical data
- Formula
- C10H9F3N2O
- Molecular weight
- 230.19 g/mol
- IUPAC name
- 5-[4-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-oxazol-2-amine
- SMILES
- C1C(OC(=N1)N)C2=CC=C(C=C2)C(F)(F)F
- InChIKey
- NMGYDYBWRZHLHR-UHFFFAOYSA-N
- XLogP
- 1.6
- Polar surface area
- 47.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 230.067
Show 2 more facts
- chemical formula
- C₁₀H₉F₃N₂O
- canonical SMILES
- C1C(OC(=N1)N)C2=CC=C(C=C2)C(F)(F)F
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Fluminorex is a centrally acting sympathomimetic which is related to other drugs such as aminorex and pemoline. It was developed as an appetite suppressant by McNeil Laboratories in the 1950s. ==Synthesis== class=skin-invert-image|500px|thumb|center|Synthesis: Patent (Ex XV): 2-amino-1-[4-(trifluoromethyl)phenyl]ethanol [776-02-3] (1) cyanogen bromide [506-68-3] (2)
==See also== 4'-Fluoro-4-methylaminorex 4-Methylaminorex Aminorex Clominorex Cyclazodone Fenozolone Pemoline Thozalinone
Excerpted from Wikipedia’s “fluminorex” article, available under the CC BY-SA 4.0 licence.