Structure via PubChem · Public domain (PubChem)
Fluvoxamin
Sign in to saveAlso known as Luvox®, U-23000, Fluvoxamine, Fluvoxaminum, Fluvoxamina
organische Verbindung, Arzneimittel
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 443824781
- Drug.image
- Fluvoxamine.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- FLUVOXAMINE_3d-ball-and-stick.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 276
- Drug.pronounce
- UK: US:
- Drug.tradename
- Luvox, others
- Drug.MedlinePlus
- a695004
- Drug.DailyMedID
- Fluvoxamine
- Drug.pregnancy_AU
- C
- Drug.routes_of_administration
- By mouth
- Drug.class
- Selective serotonin reuptake inhibitor (SSRI)
- Drug.ATC_prefix
- N06
- Drug.ATC_suffix
- AB08
- Drug.legal_AU
- S4
via Wikipedia infobox
Chemical data
- Formula
- C15H21F3N2O2
- Molecular weight
- 318.33 g/mol
- IUPAC name
- 2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]oxyethanamine
- SMILES
- COCCCC/C(=N\OCCN)/C1=CC=C(C=C1)C(F)(F)F
- InChIKey
- CJOFXWAVKWHTFT-XSFVSMFZSA-N
- XLogP
- 2.6
- Polar surface area
- 56.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1994
- Admin. routes
- oral
- Indications
- neoplasm, autism, obsessive-compulsive disorder, panic disorder
via ChEMBL · EBI
Research
3,573 papers- Fluvoxamine for symptomatic outpatients with COVID-19.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022
- [Fluvoxamine in the treatment of anxiety-depressive spectrum disorders].Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2024
- Adjunctive Fluvoxamine for Schizophrenia: A Meta-analysis of Randomized Double-Blind, Placebo-Controlled Trials.Journal of clinical psychopharmacology · 2020
- Fluvoxamine for the Early Treatment of SARS-CoV-2 Infection: A Review of Current Evidence.Drugs · 2021
- Lack of Benefit of Fluvoxamine for COVID-19.JAMA · 2023
via PubMed
Wikidata facts
- Mass
- 318.156
- Has use
- medication
Show 10 more facts
- chemical formula
- C₁₅H₂₁F₃N₂O₂
- significant drug interaction
- (RS)-citalopram
- medical condition treated
- obsessive-compulsive disorder
- isomeric SMILES
- COCCCC/C(=N\OCCN)/C1=CC=C(C=C1)C(F)(F)F
- canonical SMILES
- COCCCCC(=NOCCN)C1=CC=C(C=C1)C(F)(F)F
- World Health Organisation international non-proprietary name
- fluvoxamine
- Commons category
- Fluvoxamine
- defined daily dose
- 0.1
- physically interacts with
- solute carrier family 6 member 4
- stylized name
- fluvoxaMINE
Sources (8)
via Wikidata · CC0
Article · Deutsch
Fluvoxamin ist ein Antidepressivum aus der Gruppe der selektiven Serotonin-Wiederaufnahmehemmer (SSRI). Es wird besonders zur Behandlung von Zwangsstörungen, seltener aber auch bei Depressionen oder Angststörungen eingesetzt. Besonders im Vergleich zu anderen Antidepressiva wie Citalopram, Fluoxetin, oder anderen SSRI (und SSNRI), ist Fluvoxamin heute eher unpopulär. In klinischen Versuchen zeigte Fluvoxamin zunächst eine Wirkung gegen COVID-19, die jedoch in weiteren Studien nicht bestätigt werden konnte. Zur Behandlung von COVID-19 ist es nicht zugelassen.
Abstract from DBpedia / Wikipedia · CC BY-SA