Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C15H18BrN3O3
- Molecular weight
- 368.23 g/mol
- IUPAC name
- 4-[6-imino-3-(4-methoxyphenyl)pyridazin-1-yl]butanoic acid;hydrobromide
- SMILES
- COC1=CC=C(C=C1)C2=NN(C(=N)C=C2)CCCC(=O)O.Br
- InChIKey
- GFZHNFOGCMEYTA-UHFFFAOYSA-N
- Polar surface area
- 86 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
27 papers- Central GABAA and GABAB receptor modulation of basal and stress-induced plasma interleukin-6 levels in mice.The Journal of pharmacology and experimental therapeutics · 1998
- Subtype specificity of gamma-aminobutyric acid type A receptor antagonism by clozapine.Naunyn-Schmiedeberg's archives of pharmacology · 1995
- GABAA receptor antagonism in the extended amygdala decreases ethanol self-administration in rats.European journal of pharmacology · 1995
- The differential antagonism by bicuculline and SR95531 of pentobarbitone-induced currents in cultured hippocampal neurons.European journal of pharmacology · 1996
- Evidence for a non-GABAergic action of quaternary salts of bicuculline on dopaminergic neurones.Neuropharmacology · 1997
via PubMed
Wikidata facts
- Subclass of
- carboxylic acid
- Has part
- bromine
- Mass
- 367.053
Show 3 more facts
- chemical formula
- C₁₅H₁₈BrN₃O₃
- canonical SMILES
- COC1=CC=C(C=C1)C2=NN(C(=N)C=C2)CCCC(=O)O.Br
- Commons category
- Gabazine
Sources (2)
via Wikidata · CC0
Article · Deutsch
Gabazin (SR-95531) ist ein selektiver, potenter allosterischer GABAA-Rezeptor-Antagonist, der von der Firma Sanofi Recherche, heute Sanofi 1986 entwickelt und vorgestellt wurde.
Abstract from DBpedia / Wikipedia · CC BY-SA