EntityQ412690· pop 28· linked from 678 articles

galantamine

Galantamine is a type of acetylcholinesterase inhibitor. It is an alkaloid extracted from the bulbs and flowers of Galanthus nivalis (common snowdrop), Galanthus caucasicus (Caucasian snowdrop), Galanthus woronowii (Voronov's snowdrop), and other members of the family Amaryllidaceae, such as Narcissus (daffodil), Leucojum aestivum (snowflake), and Lycoris including Lycoris radiata (red spider lily). It can also be produced synthetically.

Key facts

Drug.Watchedfields: changed
Drug.caption2: 3D representation of a galantamine molecule
Drug.class: Acetylcholinesterase inhibitor
Drug.verifiedrevid: 461118063
Drug.image: Galantamine.svg
Drug.image_class: skin-invert-image
Drug.caption: Molecular structure of galantamine
Drug.image2: Galantamine_3D_Ball-and-Stick.png
Drug.image_class2: bg-transparent
Drug.width2: 276
Drug.tradename: Razadyne, others
Drug.MedlinePlus: a699058
Drug.DailyMedID: Razadyne
Drug.pregnancy_AU: B1
Drug.metabolism: Liver partially CYP450:CYP2D6/3A4 substrate
Drug.elimination_half life: 7 hours
Drug.excretion: Kidney (95%, of which 32% unchanged), fecal (5%)
Drug.IUPHAR_ligand: 6693

via Wikipedia infobox

Article

14 sections

Contents

Medical uses
Alzheimer's disease
Side effects
Pharmacology
Pharmacokinetics
Metabolism
Drug interactions
Extraction and synthesis
Research
Organophosphate poisoning
Autism
Anesthesia
Oneirogen
References

Galantamine is used clinically for treating early-stage Alzheimer's disease and memory impairments, although it has had limited success with the more advanced condition of dementia.