GFER
Sign in to saveAlso known as ALR, ERV1, HERV1, HPO, HPO1, HPO2, HSS, growth factor, augmenter of liver regeneration
Growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae), also known as GFER, or Hepatopoietin is a protein which in humans is encoded by the GFER gene. This gene is also known as essential for respiration and vegatative growth, augmenter of liver regeneration, and growth factor of Erv1-like/Hepatic regenerative stimulation substance.
In the Vinony graph
Vinony's link graph records 8 inbound references to GFER, and connects out to PubMed, human chromosome 16 and Ensembl genome database project.
Vinony files it under Genes on human chromosome 16 and Long stubs with short prose.
Vinony links it to 5 Wikipedia language editions.
Gene data
GFER- Name
- growth factor, augmenter of liver regeneration
- Type
- protein-coding
- Position
- 1,983,699–1,987,749 (+)
- Aliases
- ALR, ERV1, HERV1, HPO, HPO1, HPO2, HSS, MMCHD, MPMCD
- Ensembl
- ENSG00000291944
- RefSeq RNA
- NM_005262.3
- RefSeq protein
- NP_005253.3
The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
growth factor, augmenter of liver regeneration
- Symbol
- GFER
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:1,983,699-1,987,749
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- exact match
- identifiers.org/ncbigene/2671
- HomoloGene ID
- 55884
- found in taxon
- Homo sapiens
- genomic end
- 2037750
- genomic start
- 1984193
- chromosome
- human chromosome 16
- cytogenetic location
- 16p13.3
- expressed in
- gastrocnemius muscle
via Wikidata · CC0
~2 min read
Encyclopedic overview
7 sectionsContents
- Structure
- Genomics
- Function
- Clinical significance
- Interactions
- References
- Further reading
Growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae), also known as GFER, or Hepatopoietin is a protein which in humans is encoded by the GFER gene. This gene is also known as essential for respiration and vegatative growth, augmenter of liver regeneration, and growth factor of Erv1-like/Hepatic regenerative stimulation substance.
== Structure == The GFER gene is located on the p arm of chromosome 16 at position 13.3 and it spans 3,600 base pairs. The GFER gene produces a 15.4 kDa protein composed of 130 amino acids. The structure of the protein is a homodimer which has been found to be fairly similar to the scERV1 protein of yeast.
Excerpted from Wikipedia’s “GFER” article, available under the CC BY-SA 4.0 licence.