GGA1
Sign in to saveAlso known as golgi associated, gamma adaptin ear containing, ARF binding protein 1
ADP-ribosylation factor-binding protein GGA1 is a protein that in humans is encoded by the GGA1 gene.
Gene data
GGA1- Name
- golgi associated, gamma adaptin ear containing, ARF binding protein 1
- Type
- protein-coding
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
- Image
- Protein GGA1 PDB 1j2j.png
Show 6 more facts
- HomoloGene ID
- 39250
- exact match
- identifiers.org/ncbigene/26088
- genomic start
- 37608725
- genomic end
- 38029571
- cytogenetic location
- 22q13.1
- Commons category
- ADP-ribosylation factor binding protein Gga1
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ADP-ribosylation factor-binding protein GGA1 is a protein that in humans is encoded by the GGA1 gene.
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.