GGA2
Sign in to saveAlso known as VEAR, golgi associated, gamma adaptin ear containing, ARF binding protein 2
ADP-ribosylation factor-binding protein GGA2 is a protein that in humans is encoded by the GGA2 gene.
Gene data
GGA2- Name
- golgi associated, gamma adaptin ear containing, ARF binding protein 2
- Type
- protein-coding
- Aliases
- VEAR
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
- Image
- Protein GGA2 PDB 1mhq.png
Show 5 more facts
- exact match
- identifiers.org/ncbigene/23062
- HomoloGene ID
- 22860
- genomic end
- 23533316
- genomic start
- 23474863
- cytogenetic location
- 16p12.2
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
ADP-ribosylation factor-binding protein GGA2 is a protein that in humans is encoded by the GGA2 gene.
== Function ==