GGA2

Also known as VEAR, golgi associated, gamma adaptin ear containing, ARF binding protein 2

ADP-ribosylation factor-binding protein GGA2 is a protein that in humans is encoded by the GGA2 gene.

In the Vinony graph

Within Vinony's link graph, GGA2 is referenced by 5 other articles, and connects out to PubMed, Ensembl genome database project and protein.

It is catalogued under the topic Genes on human chromosome 16.

Its subject is documented across 4 Wikipedia language editions.

Gene data

GGA2

Name: golgi associated, gamma adaptin ear containing, ARF binding protein 2
Type: protein-coding
Position: 23,462,213–23,521,995 (−)
Aliases: VEAR
Ensembl: ENSG00000103365
RefSeq RNA: NM_015044.4, NM_138640.1, XM_047433801.1, XM_047433802.1, XM_054379851.1
RefSeq protein: NP_055859.1, XP_047289757.1, XP_047289758.1, XP_054235826.1, XP_054235827.1

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. [provided by RefSeq, Jul 2008].