glyburide

Also known as glibenclamide, 5-chloro-N-{2-[4-({[(cyclohexylamino)carbonyl]amino}sulfonyl)phenyl]ethyl}-2-methoxybenzamide, 1-{p-[2-(5-chloro-2-methoxybenzamido)ethyl]benzenesulfonyl}-3-cyclohexylurea, 1-({p-[2-(5-chloro-o-anisamido)ethyl]phenyl}sulfonyl)-3-cyclohexylurea

Glibenclamide, also known as glyburide (U.S. English), is an antidiabetic medication used to treat type 2 diabetes. It is recommended that it be taken together with diet and exercise. It may be used with other antidiabetic medication. It is not recommended for use by itself in type 1 diabetes. It is taken by mouth.

Key facts

Drug.Watchedfields: changed
Drug.verifiedrevid: 461120828
Drug.image: Glibenclamide.svg
Drug.image_class: skin-invert-image
Drug.width: 275
Drug.image2: Glibenclamide-4YVP-ball-and-stick.png
Drug.image_class2: bg-transparent
Drug.USAN: Glyburide
Drug.tradename: Diabeta, Glynase, Micronase, others
Drug.MedlinePlus: a684058
Drug.DailyMedID: Glyburide
Drug.pregnancy_AU: C
Drug.routes_of_administration

~4 min read

Article

9 sections

Contents

Medical uses
Side effects
Contraindications
Pregnancy and breastfeeding
Mechanism of action
History
Society and culture
Brand names
References

Common side effects include nausea and heartburn. Serious side effects may include angioedema and low blood sugar. It is generally not recommended during pregnancy but can be used during breastfeeding. It is in the sulfonylureas class of medications and works by increasing the release of insulin from the pancreas.