GNAQ
Sign in to saveAlso known as CMC1, G-ALPHA-q, GAQ, SWS, G protein subunit alpha q
Guanine nucleotide-binding protein G(q) subunit alpha is a protein that in humans is encoded by the GNAQ gene. Together with GNA11 (its paralogue), it functions as a Gq alpha subunit.
In the Vinony graph
Vinony's link graph records 310 inbound references to GNAQ, and connects out to PubMed, Online Mendelian Inheritance in Man and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 9.
Vinony links it to 6 Wikipedia language editions.
Gene data
GNAQ- Name
- G protein subunit alpha q
- Type
- protein-coding
- Position
- 77,716,097–78,032,500 (−)
- Aliases
- CMAL, G-ALPHA-q, GAQ, SWS
- Ensembl
- ENSG00000156052
- RefSeq RNA
- NM_002072.5, XM_047423239.1, XM_047423240.1, XM_054362755.1, XM_054362756.1
- RefSeq protein
- NP_002063.2, XP_047279195.1, XP_047279196.1, XP_054218730.1, XP_054218731.1
This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
G protein subunit alpha q
- Symbol
- GNAQ
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:77,716,097-78,032,500
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein GNAQ PDB 2bcj.png
Show 9 more facts
- exact match
- identifiers.org/ncbigene/2776
- HomoloGene ID
- 1566
- found in taxon
- Homo sapiens
- genomic end
- 78031811
- genomic start
- 77716097
- chromosome
- human chromosome 9
- cytogenetic location
- 9q21.2
- genetic association
- Sturge–Weber syndrome
- expressed in
- subthalamic nucleus
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- See also
- References
- Further reading
Guanine nucleotide-binding protein G(q) subunit alpha is a protein that in humans is encoded by the GNAQ gene. Together with GNA11 (its paralogue), it functions as a Gq alpha subunit.
== Function ==
Excerpted from Wikipedia’s “GNAQ” article, available under the CC BY-SA 4.0 licence.