GNAQ
Sign in to saveAlso known as CMC1, G-ALPHA-q, GAQ, SWS, G protein subunit alpha q
Guanine nucleotide-binding protein G(q) subunit alpha is a protein that in humans is encoded by the GNAQ gene. Together with GNA11 (its paralogue), it functions as a Gq alpha subunit.
Gene data
GNAQ- Name
- G protein subunit alpha q
- Type
- protein-coding
- Position
- 77,716,097–78,031,972 (−)
- Aliases
- CMAL, G-ALPHA-q, GAQ, SWS
- Ensembl
- ENSG00000156052
- RefSeq RNA
- NM_002072.5, XM_047423239.1, XM_047423240.1, XM_054362755.1, XM_054362756.1
- RefSeq protein
- NP_002063.2, XP_047279195.1, XP_047279196.1, XP_054218730.1, XP_054218731.1
This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
G protein subunit alpha q
- Symbol
- GNAQ
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:77,716,097-78,032,500
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein GNAQ PDB 2bcj.png
Show 5 more facts
- exact match
- identifiers.org/ncbigene/2776
- HomoloGene ID
- 1566
- genomic end
- 78031811
- genomic start
- 77716097
- cytogenetic location
- 9q21.2
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Interactions
- See also
- References
- Further reading
Guanine nucleotide-binding protein G(q) subunit alpha is a protein that in humans is encoded by the GNAQ gene. Together with GNA11 (its paralogue), it functions as a Gq alpha subunit.
== Function ==