GSDME
Sign in to saveAlso known as ICERE-1, DFNA5, DFNA5, deafness associated tumor suppressor, gasdermin E
Non-syndromic hearing impairment protein 5 is a protein that in humans is encoded by the DFNA5 gene.
Gene data
GSDME- Name
- gasdermin E
- Type
- protein-coding
- Position
- 24,698,301–24,757,992 (−)
- Aliases
- DFNA5, ICERE-1
- Ensembl
- ENSG00000105928
- RefSeq RNA
- NM_001127453.2, NM_001127454.2, NM_001438059.1, NM_004403.3, XM_024446670.2
- RefSeq protein
- NP_001120925.1, NP_001120926.1, NP_001424988.1, NP_004394.1, XP_024302438.1
Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
gasdermin E
- Symbol
- GSDME
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:24,698,301-24,757,992
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- References
- Further reading
- External links
Non-syndromic hearing impairment protein 5 is a protein that in humans is encoded by the DFNA5 gene.
== Function ==
Excerpted from Wikipedia’s “GSDME” article, available under the CC BY-SA 4.0 licence.