TRAF5
Sign in to saveAlso known as MGC:39780, RNF84, TNF receptor associated factor 5
TNF receptor-associated factor 5 is a protein that in humans is encoded by the TRAF5 gene.
In the Vinony graph
Vinony's link graph records 38 inbound references to TRAF5, and connects out to PubMed, interferon gamma and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 1.
Vinony links it to 5 Wikipedia language editions.
Gene data
TRAF5- Name
- TNF receptor associated factor 5
- Type
- protein-coding
- Position
- 211,326,325–211,375,117 (+)
- Aliases
- MGC:39780, RNF84
- Ensembl
- ENSG00000082512
- RefSeq RNA
- NM_001033910.3, NM_001319207.2, NM_004619.4, NM_145759.3, XM_011509957.4
- RefSeq protein
- NP_001029082.1, NP_001306136.1, NP_004610.1, NP_665702.1, XP_011508259.2
The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
TNF receptor associated factor 5
- Symbol
- TRAF5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:211,326,325-211,375,117
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 27079
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7188
- genomic end
- 211548288
- genomic start
- 211499957
- chromosome
- human chromosome 1
- cytogenetic location
- 1q32.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
TNF receptor-associated factor 5 is a protein that in humans is encoded by the TRAF5 gene.
== Function ==
Excerpted from Wikipedia’s “TRAF5” article, available under the CC BY-SA 4.0 licence.