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GeneQ18026887· pop 5· linked from 6 articles

Also known as HGFA, HGF activator

Hepatocyte growth factor activator is a protein that in humans is encoded by the HGFAC gene.

Gene data

HGFAC
Name
HGF activator
Type
protein-coding
Aliases
HGFA

This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].

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Wikidata facts

Image
Protein HGFAC PDB 1ybw.png
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HomoloGene ID
1170
genomic end
3449486
genomic start
3441968
cytogenetic location
4p16.3
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Hepatocyte growth factor activator is a protein that in humans is encoded by the HGFAC gene.

The protein encoded by this gene, belongs to peptidase family S1. It is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form.

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