Histona

Also known as histones

familia de proteínas que empaquetan el ADN en nucleosomas y cromatina

AI overview

Histones are proteins found in the nuclei of eukaryotic cells that act as spools around which DNA winds, helping to organize and protect the genetic material. They are essential for preventing DNA from becoming tangled, shielding it from damage, and controlling which genes are turned on or off in cells.

AI-generated from the Wikipedia summary — may contain errors.

Research

160,348 papers

Lateral Thinking: How Histone Modifications Regulate Gene Expression.ReviewTrends in genetics : TIG · 2016Lawrence M, Daujat S, Schneider RDOI: 10.1016/j.tig.2015.10.007
Erasers of histone acetylation: the histone deacetylase enzymes.ReviewCold Spring Harbor perspectives in biology · 2014Seto E, Yoshida MDOI: 10.1101/cshperspect.a018713
Histone variants at a glance.ReviewJournal of cell science · 2021Talbert PB, Henikoff SDOI: 10.1242/jcs.244749
Histone variants: The bricks that fit differently.ReviewThe Journal of biological chemistry · 2025Hegazy YA, Dhahri H, El Osmani N et al.DOI: 10.1016/j.jbc.2024.108048
Histone acetyltransferase 1 is a succinyltransferase for histones and non-histones and promotes tumorigenesis.EMBO reports · 2021Yang G, Yuan Y, Yuan H et al.DOI: 10.15252/embr.202050967
H3-H4 histone chaperones and cancer.ReviewCurrent opinion in genetics & development · 2022Ray-Gallet D, Almouzni GDOI: 10.1016/j.gde.2022.101900
Histone degradation by the proteasome regulates chromatin and cellular plasticity.ReviewThe FEBS journal · 2022Shmueli MD, Sheban D, Eisenberg-Lerner A et al.DOI: 10.1111/febs.15903
Primate-specific histone variants.ReviewGenome · 2021Ding D, Nguyen TT, Pang MYH et al.DOI: 10.1139/gen-2020-0094

via PubMed

Wikidata facts

Subclass of: protein
Image: Nucleosome structure-2.png

Show 1 more fact

different from: Histon

Sources (6)

via Wikidata · CC0

Article · Español

Las histonas son proteínas básicas, de baja masa molecular, y están muy conservadas (en términos evolutivos) entre los eucariontes. Forman la cromatina junto con el ADN sobre la base, entre otras; de unas unidades conocidas como nucleosomas. La cromatina reduce el tamaño lineal del ADN dentro del núcleo, compactándolo. La cromatina está formada por ADN y varios tipos de proteínas, las principales de las cuales son las histonas.

Abstract from DBpedia / Wikipedia · CC BY-SA