Structure via PubChem · Public domain (PubChem)
Key facts
- Drug.Verifiedfields
- changed
- Drug.verifiedrevid
- 461774343
- Drug.IUPAC_name
- (1R,5S,6R,7S)-4-Hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-en-1-yl)-6-(4-methylpent-3-en-1-yl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-3-ene-2,9-dion
- Drug.image
- Hyperforin2DACS.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 225
- Drug.image2
- Hyperforin3Dan2.gif
- Drug.image_class2
- bg-transparent
- Drug.width2
- 200
- Drug.legal_UK
- GSL
- Drug.legal_US
- OTC
- Drug.legal_status
- unscheduled in most countries, with the notable exception of Ireland (Rx-only)
- Drug.dependency_liability
- None
- Drug.routes_of_administration
- Oral
- Drug.metabolism
- Hepatic and CYP3A & CYP2B
- Drug.IUPHAR_ligand
- 2764
- Drug.CAS_number
- 11079-53-1
- Drug.PubChem
- 114787
via Wikipedia infobox
Chemical data
- Formula
- C35H52O4
- Molecular weight
- 536.8 g/mol
- IUPAC name
- (1R,5R,7S,8R)-4-hydroxy-8-methyl-3,5,7-tris(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)-1-(2-methylpropanoyl)bicyclo[3.3.1]non-3-ene-2,9-dione
- SMILES
- CC(C)C(=O)[C@]12C(=O)C(=C([C@](C1=O)(C[C@@H]([C@@]2(C)CCC=C(C)C)CC=C(C)C)CC=C(C)C)O)CC=C(C)C
- InChIKey
- KGSZHKRKHXOAMG-HQKKAZOISA-N
- XLogP
- 9.6
- Polar surface area
- 71.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 536.386560144
Show 5 more facts
- canonical SMILES
- CCCC(=O)C12C(=O)C(=C(C(C1=O)(CC(C2(C)CCC=C(C)C)CC=C(C)C)CC=C(C)C)O)CC=C(C)C
- chemical formula
- C₃₅H₅₂O₄
- Commons category
- Hyperforin
- found in taxon
- Hypericum elodes
- isomeric SMILES
- CC(C)=CCC[C@]1(C)[C@@H](CC=C(C)C)C[C@@]2(CC=C(C)C)C(=O)[C@]1(C(=O)C(C)C)C(=O)C(CC=C(C)C)=C2O
via Wikidata · CC0
Article · Español
La hiperforina es un derivado de que se extrae de la hierba de San Juan al que se atribuyen efectos sobre los neurotransmisores y las células nerviosas en el cerebro. Inhibe la recaptura de dopamina, noradrenalina, ácido gamma-aminobutírico y glutamato. Por ello se utiliza en el tratamiento de enfermedades mentales y degenerativas, como el Alzheimer, la depresión y ansiedad leve, la demencia vascular, el insomnio, entre otras.
Abstract from DBpedia / Wikipedia · CC BY-SA