Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C16H16ClN3O3S
- Molecular weight
- 365.8 g/mol
- IUPAC name
- 4-chloro-N-(2-methyl-2,3-dihydroindol-1-yl)-3-sulfamoylbenzamide
- SMILES
- CC1CC2=CC=CC=C2N1NC(=O)C3=CC(=C(C=C3)Cl)S(=O)(=O)N
- InChIKey
- NDDAHWYSQHTHNT-UHFFFAOYSA-N
- XLogP
- 2.9
- Polar surface area
- 101 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1983
- Admin. routes
- oral
- Indications
- hypertension, cardiovascular disease, congestive heart failure, preeclampsia
via ChEMBL · EBI
Research
1,577 papers- Indapamide: a review.South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde · 1983
- Not So Innocent Indapamide.Journal of Ayub Medical College, Abbottabad : JAMC · 2023
- Indapamide sustained release: a review of its use in the treatment of hypertension.Drugs · 2006
- Perindopril 2mg/indapamide 0.625mg. Fixed low-dose combination.Drugs · 1999
- The effect of indapamide vs. bendroflumethiazide for primary hypertension: a systematic review.British journal of clinical pharmacology · 2019
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 365.06009
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₆H₁₆ClN₃O₃S
- medical condition treated
- arterial hypertension
- canonical SMILES
- CC1CC2=CC=CC=C2N1NC(=O)C3=CC(=C(C=C3)Cl)S(=O)(=O)N
- defined daily dose
- 2.5
- significant drug interaction
- bromocriptine
- Commons category
- Indapamide
Sources (8)
via Wikidata · CC0
Article · Italiano
L’indapamide è una molecola dotata di attività diuretica, che fa parte della famiglia dei sulfonamidi. La sua molecola contiene sia una porzione polare sulfamide clorobenzamide sia una porzione liposolubile metilindolina. Viene considerata appartenente alla classe delle sostanze tiazidi-simili, essendo un benzamide-sulfonamide-indolo, ma mancando dell'anello tiazidico.In clinica viene utilizzata come diuretico e come farmaco contro l'ipertensione.
Abstract from DBpedia / Wikipedia · CC BY-SA