Structure via PubChem · Public domain (PubChem)
perindopril
Sign in to saveAlso known as Coversyl®, Preterax®, S-9490, (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid, (2S,3AS,7as)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid, Perindoprilum
Perindopril is a medication used to treat high blood pressure, heart failure, or stable coronary artery disease.
Chemical data
- Formula
- C19H32N2O5
- Molecular weight
- 368.5 g/mol
- IUPAC name
- (2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid
- SMILES
- CCC[C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)O
- InChIKey
- IPVQLZZIHOAWMC-QXKUPLGCSA-N
- XLogP
- 0.9
- Polar surface area
- 95.9 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Research
2,560 papers- Perindopril.Expert opinion on pharmacotherapy · 2006
- Perindopril: A comprehensive profile.Profiles of drug substances, excipients, and related methodology · 2026
- Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study).Lancet (London, England) · 2003
- Perindopril.Heart disease (Hagerstown, Md.) · 2000
- Perindopril for the treatment of hypertension.Expert opinion on pharmacotherapy · 2011
via PubMed
Wikidata facts
- Mass
- 368.231
- Official website
- www.coversyl.com
Show 6 more facts
- chemical formula
- C₁₉H₃₂N₂O₅
- isomeric SMILES
- CCC[C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)O
- canonical SMILES
- CCCC(C(=O)OCC)NC(C)C(=O)N1C2CCCCC2CC1C(=O)O
- World Health Organisation international non-proprietary name
- perindopril
- defined daily dose
- 4
- Commons category
- Perindopril
Sources (8)
via Wikidata · CC0
~9 min read
Article
14 sectionsContents
- Medical uses
- Combination therapy
- With indapamide
- With amlodipine
- Warning and adverse effects
- Precautions
- Side effects
- Composition
- Society and culture
- Brand names
- Marketing
- References
- Further reading
- External links
{{Drugbox | Verifiedfields = changed | verifiedrevid = 464199140 | IUPAC_name = (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic acid | image = Perindopril 2.svg | image_class = skin-invert-image | width = 222
| caption = Above: molecular structure of perindopril Below: 3D representation of a perindopril molecule | image2 = Perindopril 3D.png | image_class2 = bg-transparent | tradename = Coversyl, Coversum, Aceon | Drugs.com = Perindopril Monograph | DailyMedID = Perindopril | MedlinePlus = Perindopril | routes_of_administration = By mouth | legal_CA = Rx-only | legal_CA_comment = | legal_UK = POM | legal_US = Rx-only