INHBB
Sign in to saveAlso known as inhibin beta B subunit, inhibin subunit beta B
Inhibin, beta B, also known as INHBB, is a protein which in humans is encoded by the INHBB gene. INHBB is a subunit of both activin and inhibin, two closely related glycoproteins with opposing biological effects.
Gene data
INHBB- Name
- inhibin subunit beta B
- Type
- protein-coding
- Position
- 120,344,814–120,351,803 (+)
- Ensembl
- ENSG00000163083
- RefSeq RNA
- NM_002193.4
- RefSeq protein
- NP_002184.2
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. Polymorphisms near this gene are associated with pre-eclampsia in female human patients. [provided by RefSeq, Aug 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
inhibin subunit beta B
- Symbol
- INHBB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:120,344,814-120,351,803
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 1654
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3625
- genomic end
- 120351803
- genomic start
- 120346136
- chromosome
- human chromosome 2
- cytogenetic location
- 2q14.2
Sources (3)
via Wikidata · CC0
~3 min read
Encyclopedic overview
8 sectionsContents
- Function
- Inhibin
- Activin
- Tissue distribution
- Receptors
- Cancer
- References
- Further reading
Inhibin, beta B, also known as INHBB, is a protein which in humans is encoded by the INHBB gene. INHBB is a subunit of both activin and inhibin, two closely related glycoproteins with opposing biological effects.
== Function ==
Excerpted from Wikipedia’s “INHBB” article, available under the CC BY-SA 4.0 licence.