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Structure via PubChem · Public domain (PubChem)
iodipamide
Sign in to saveAlso known as Cholografin, Adipiodone, Adipiodona, Adipiodonum, 3,3'-(adipoyldiimino)bis(2,4,6-triiodobenzoic acid)
Adipiodone (INN, or iodipamide; trade names Cholografin and Biligrafin) is a pharmaceutical drug used as a radiocontrast agent in X-ray imaging. It was introduced in the 1950s.
Chemical data
- Formula
- C20H14I6N2O6
- Molecular weight
- 1139.8 g/mol
- IUPAC name
- 3-[[6-(3-carboxy-2,4,6-triiodoanilino)-6-oxohexanoyl]amino]-2,4,6-triiodobenzoic acid
- SMILES
- C1=C(C(=C(C(=C1I)NC(=O)CCCCC(=O)NC2=C(C=C(C(=C2I)C(=O)O)I)I)I)C(=O)O)I
- InChIKey
- FFINMCNLQNTKLU-UHFFFAOYSA-N
- XLogP
- 5.5
- Polar surface area
- 133 Ų
- H-bond donors
- 4
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1982
- Admin. routes
- parenteral, topical
via ChEMBL · EBI
Research
806 papers- Biliary excretion of iodipamide.Gastroenterology · 1975
- The choleretic effect of iodipamide.The Journal of clinical investigation · 1975
- Meglumine iodipamide (Cholografin) hepatotoxicity.Annals of internal medicine · 1977
- Saturation kinetics of iodipamide.Investigative radiology · 1977
- Iodipamide kinetics: capacity-limited biliary excretion with simultaneous pseudo-first-order renal excretion.Journal of pharmaceutical sciences · 1977
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 1139.512
- Has use
- medication
Show 3 more facts
- canonical SMILES
- C1=C(C(=C(C(=C1I)NC(=O)CCCCC(=O)NC2=C(C=C(C(=C2I)C(=O)O)I)I)I)C(=O)O)I
- chemical formula
- C₂₀H₁₄I₆N₂O₆
- subject has role
- contrast agent
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
1 sectionsContents
- References
{{Drugbox | verifiedrevid = 477242817 | IUPAC_name = 3-{5-[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]pentanamido}-2,4,6-triiodobenzoic acid | image = Adipiodone.png | image_class = skin-invert-image
| tradename = Cholografin, Biligrafin | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = Rx-only | routes_of_administration =
Excerpted from Wikipedia’s “iodipamide” article, available under the CC BY-SA 4.0 licence.