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iproheptine

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EntityQ5928539· pop 7· linked from 1,153 articles

iproheptine

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Iproheptine, also known as '''N-isopropyl-1,5-dimethylhexylamine or N-isopropyloctodrine and sold under the brand names Metron and Susat''', is a nasal decongestant which has been marketed in Japan. It is described as a vasoconstrictor and antihistamine. The drug is available over-the-counter in Japan.

Chemical data

Formula
C11H25N
Molecular weight
171.32 g/mol
IUPAC name
6-methyl-N-propan-2-ylheptan-2-amine
SMILES
CC(C)CCCC(C)NC(C)C
InChIKey
NKGYBXHAQAKSSG-UHFFFAOYSA-N
XLogP
3.6
Polar surface area
12 Ų
H-bond donors
1
H-bond acceptors
1
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
171.199
Show 2 more facts
canonical SMILES
CC(C)CCCC(C)NC(C)C
chemical formula
C₁₁H₂₅N
Sources (2)

via Wikidata · CC0

~3 min read

Encyclopedic overview

10 sections
Contents
  • Pharmacology
  • Pharmacodynamics
  • Pharmacokinetics
  • Chemistry
  • History
  • Society and culture
  • Names
  • Availability
  • See also
  • References

Iproheptine, also known as '''N-isopropyl-1,5-dimethylhexylamine or N-isopropyloctodrine and sold under the brand names Metron and Susat', is a nasal decongestant which has been marketed in Japan. It is described as a vasoconstrictor and antihistamine. The drug is available over-the-counter in Japan.

==Pharmacology== ===Pharmacodynamics=== Iproheptine is described as a decongestant, vasoconstrictor, and antihistamine. Its pharmacology was characterized in a series of several preclinical studies published in the 1960s.

Excerpted from Wikipedia’s “iproheptine” article, available under the CC BY-SA 4.0 licence.

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