ispronicline
Sign in to saveAlso known as AZD3480, TC 1734, RJR 1734
Ispronicline (TC-1734, AZD-3480) is an experimental drug which acts as a partial agonist at neural nicotinic acetylcholine receptors. It progressed to phase II clinical trials for the treatment of dementia and Alzheimer's disease, but is no longer under development.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 234.173
Show 5 more facts
- chemical formula
- C₁₄H₂₂N₂O
- canonical SMILES
- CC(C)OC1=CN=CC(=C1)C=CCC(C)NC
- isomeric SMILES
- C[C@@H](C/C=C/C1=CC(=CN=C1)OC(C)C)NC
- Commons category
- Ispronicline
- subject has role
- nootropic
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Encyclopedic overview
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- See also
- References
Ispronicline (TC-1734, AZD-3480) is an experimental drug which acts as a partial agonist at neural nicotinic acetylcholine receptors. It progressed to phase II clinical trials for the treatment of dementia and Alzheimer's disease, but is no longer under development.
It has also progressed to phase II as a potential treatment for ADHD. With dosages of 50 mg/day showing a significant improvement in ADHD symptoms
Excerpted from Wikipedia’s “ispronicline” article, available under the CC BY-SA 4.0 licence.