KIF17

Also known as 5930435E01Rik, AW492270, Kif17b, mKIAA1405, KIF3X, KLP-2, OSM-3

Kinesin-like protein KIF17 is a protein that in humans is encoded by the KIF17 gene. KIF17 and its close relative, C. elegans OSM-3, are members of the kinesin-2 family of plus-end directed microtubule-based motor proteins. In contrast to heterotrimeric kinesin-2 motors, however, KIF17 and OSM-3 form distinct homodimeric complexes. Homodimeric kinesin-2 has been implicated in the transport of NMDA receptors along dendrites for delivery to the dendritic membrane, whereas both heterotrimeric and homodimeric kinesin-2 motors function cooperatively in anterograde intraflagellar transport (IFT) and

In the Vinony graph

Within Vinony's link graph, KIF17 is referenced by 272 other articles, and connects out to Q180686, human chromosome 1 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 1.

Its subject is documented across 5 Wikipedia language editions.

Gene data

KIF17

Name: kinesin family member 17
Type: protein-coding
Position: 20,664,011–20,718,018 (−)
Aliases: KIF17B, KIF3X, KLP-2, OSM-3
Ensembl: ENSG00000117245
RefSeq RNA: NM_001122819.3, NM_001287212.2, NM_020816.4, XM_047426146.1, XM_047426147.1
RefSeq protein: NP_001116291.1, NP_001274141.1, NP_065867.2, XP_047282102.1, XP_047282103.1

Predicted to enable microtubule binding activity and plus-end-directed microtubule motor activity. Predicted to be involved in anterograde dendritic transport of neurotransmitter receptor complex and cell projection organization. Predicted to act upstream of or within microtubule-based process; protein-containing complex localization; and vesicle-mediated transport. Predicted to be located in microtubule cytoskeleton. Predicted to be part of intraciliary transport particle B and kinesin complex. Predicted to be active in cilium; microtubule cytoskeleton; and neuron projection. [provided by Alliance of Genome Resources, Apr 2022]