KIF2C

Also known as CT139, KNSL6, MCAK, kinesin family member 2C

Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene.

Gene data

KIF2C

Name: kinesin family member 2C
Type: protein-coding
Aliases: CT139, KNSL6, MCAK

This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].

via MyGene.info

Wikidata facts

Image: Protein KIF2C PDB 1v8j.png

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HomoloGene ID: 21355
exact match: identifiers.org/ncbigene/11004
genomic end: 45233439
genomic start: 45205490
cytogenetic location: 1p34.1

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Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene.

The protein encoded by this gene is a member of kinesin-like protein family, and contains common ATPase site structures such as the P-loop, Switch 1, and Switch 2. Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. center|thumb|270x270px|A ribbon and surface diagram of the KIF2C motor domain. The kinesin structure is pseudo-colored to highlight the ATPase site with a bound nucleotide. The figure then presents KIF2C binding to the tubulin dimer and finally visualizes a KIF2C motor head in the context of the microtubule filament.