KRT72
Sign in to saveAlso known as K6IRS2, K6irs, KRT6, KRT6IRS2, keratin 72, K72, CK-72
KRT72 is a keratin gene. It is responsible for hair formation, and it encodes a protein present in the inner root sheath of hair follicles.
Gene data
KRT72- Name
- keratin 72
- Type
- protein-coding
- Position
- 52,585,589–52,601,538 (−)
- Aliases
- CK-72, K6IRS2, K6irs, K72, KRT6, KRT6IRS2
- Ensembl
- ENSG00000170486
- RefSeq RNA
- NM_001146225.2, NM_001146226.2, NM_080747.3, XM_047428321.1, XM_047428322.1
- RefSeq protein
- NP_001139697.1, NP_001139698.1, NP_542785.1, XP_047284277.1, XP_047284278.1
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2009].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
keratin 72
- Symbol
- KRT72
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:52,585,589-52,601,538
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 25876
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/140807
- genomic end
- 52995322
- genomic start
- 52979373
- chromosome
- human chromosome 12
- cytogenetic location
- 12q13.13
- expressed in
- appendix
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
KRT72 is a keratin gene. It is responsible for hair formation, and it encodes a protein present in the inner root sheath of hair follicles.
== References == "KRT72 Gene - GeneCards | K2C72 Protein | K2C72 Antibody". www.genecards.org. Retrieved 2022-05-19
Excerpted from Wikipedia’s “KRT72” article, available under the CC BY-SA 4.0 licence.