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GeneQ18053062· pop 5· linked from 271 articles

Also known as CK-78, K5B, K78, Kb40, keratin 78

Keratin, type II cytoskeletal 78 is a protein that in humans is encoded by the KRT78 gene.

Gene data

KRT78
Name
keratin 78
Type
protein-coding
Aliases
CK-78, K5B, K78, Kb40

This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified. [provided by RefSeq, Jul 2008].

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Wikidata facts

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HomoloGene ID
65261
genomic end
53242876
genomic start
53231588
cytogenetic location
12q13.13
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Keratin, type II cytoskeletal 78 is a protein that in humans is encoded by the KRT78 gene.

This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.

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