KRT78
Sign in to saveAlso known as CK-78, K5B, K78, Kb40, keratin 78
Keratin, type II cytoskeletal 78 is a protein that in humans is encoded by the KRT78 gene.
Gene data
KRT78- Name
- keratin 78
- Type
- protein-coding
- Position
- 52,837,804–52,849,092 (−)
- Aliases
- CK-78, K5B, K78, Kb40
- Ensembl
- ENSG00000170423
- RefSeq RNA
- NM_001300814.1, NM_173352.4, XM_011538010.2, XM_054371363.1
- RefSeq protein
- NP_001287743.1, NP_775487.2, XP_011536312.1, XP_054227338.1
This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
keratin 78
- Symbol
- KRT78
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:52,837,804-52,849,092
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 65261
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/196374
- genomic end
- 53242876
- genomic start
- 53231588
- chromosome
- human chromosome 12
- cytogenetic location
- 12q13.13
- expressed in
- testicle
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Keratin, type II cytoskeletal 78 is a protein that in humans is encoded by the KRT78 gene.
This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.
Excerpted from Wikipedia’s “KRT78” article, available under the CC BY-SA 4.0 licence.