KRT85
Sign in to saveAlso known as ECTD4, HB5, Hb-5, K85, KRTHB5, hHb5, keratin 85
Keratin, type II cuticular Hb5 is a protein that in humans is encoded by the KRT85 gene.
Gene data
KRT85- Name
- keratin 85
- Type
- protein-coding
- Position
- 52,360,006–52,367,481 (−)
- Aliases
- ECTD4, HB5, Hb-5, K85, KRTHB5, hHb5
- Ensembl
- ENSG00000135443
- RefSeq RNA
- NM_001300810.1, NM_002283.4
- RefSeq protein
- NP_001287739.1, NP_002274.1
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
keratin 85
- Symbol
- KRT85
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:52,360,006-52,367,481
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 37603
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3891
- genomic end
- 52761265
- genomic start
- 52753790
- chromosome
- human chromosome 12
- cytogenetic location
- 12q13.13
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Keratin, type II cuticular Hb5 is a protein that in humans is encoded by the KRT85 gene.
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5.
Excerpted from Wikipedia’s “KRT85” article, available under the CC BY-SA 4.0 licence.