Structure via PubChem · Public domain (PubChem)
mavacoxib
Sign in to saveAlso known as PHA 739,521, PHA-739521
Mavacoxib (trade name Trocoxil) is a veterinary drug used to treat pain and inflammation in dogs with degenerative joint disease. It acts as a COX-2 inhibitor.
Chemical data
- Formula
- C16H11F4N3O2S
- Molecular weight
- 385.3 g/mol
- IUPAC name
- 4-[5-(4-fluorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
- SMILES
- C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)F
- InChIKey
- TTZNQDOUNXBMJV-UHFFFAOYSA-N
- XLogP
- 3.1
- Polar surface area
- 86.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 385.051
Show 5 more facts
- chemical formula
- C₁₆H₁₁F₄N₃O₂S
- canonical SMILES
- C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)F
- World Health Organisation international non-proprietary name
- mavacoxib
- Commons category
- Mavacoxib
- subject has role
- COX-2 inhibitor
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Mavacoxib (trade name Trocoxil) is a veterinary drug used to treat pain and inflammation in dogs with degenerative joint disease. It acts as a COX-2 inhibitor.
Mavacoxib, along with several other COX-2 selective inhibitors, including celecoxib, valdecoxib, and parecoxib, were discovered by a team at the Searle division of Monsanto led by John Talley.
Excerpted from Wikipedia’s “mavacoxib” article, available under the CC BY-SA 4.0 licence.