Structure via PubChem · Public domain (PubChem)
metaxalone
Sign in to saveMetaxalone, sold under the brand name Skelaxin, is a muscle relaxant medication used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions. Its exact mechanism of action is not known, but it may be due to general central nervous system depression. It is a moderately strong muscle relaxant, with relatively low incidence of side effects.
Chemical data
- Formula
- C12H15NO3
- Molecular weight
- 221.25 g/mol
- IUPAC name
- 5-[(3,5-dimethylphenoxy)methyl]-1,3-oxazolidin-2-one
- SMILES
- CC1=CC(=CC(=C1)OCC2CNC(=O)O2)C
- InChIKey
- IMWZZHHPURKASS-UHFFFAOYSA-N
- XLogP
- 2.2
- Polar surface area
- 47.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1962
- Admin. routes
- oral
via ChEMBL · EBI
Research
65 papers- Metaxalone.2012
- Metaxalone-induced Immune Hemolytic Anemia.Journal of community hospital internal medicine perspectives · 2023
- Biocatalytic Synthesis of Metaxalone and Its Analogues.Organic letters · 2023
- Choosing a skeletal muscle relaxant.American family physician · 2008
- Metaxalone (Skelaxin)-related death.Journal of analytical toxicology · 2004
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 221.105193
- Has use
- medication
Show 5 more facts
- chemical formula
- C₁₂H₁₅NO₃
- medical condition treated
- muscle cramp
- canonical SMILES
- CC1=CC(=CC(=C1)OCC2CNC(=O)O2)C
- Commons category
- Metaxalone
- found in taxon
- Caenorhabditis elegans
via Wikidata · CC0
~2 min read
Encyclopedic overview
4 sectionsContents
- Pharmacokinetics
- Assay
- References
- External links
Metaxalone, sold under the brand name Skelaxin, is a muscle relaxant medication used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions. Its exact mechanism of action is not known, but it may be due to general central nervous system depression. It is a moderately strong muscle relaxant, with relatively low incidence of side effects.
Common side effects include nausea, vomiting, drowsiness, and central nervous system (CNS) side effects, such as dizziness, headache, and irritability.
Excerpted from Wikipedia’s “metaxalone” article, available under the CC BY-SA 4.0 licence.